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Based on the deduced amino acid sequence of
2021-07-09

Based on the deduced amino Terbutaline Sulfate sequence of the catalytic subunit of rG3DH, we could find sequence features that are highly conserved in FAD-harboring dehydrogenase, which include FAD binding motif and sequential cysteine residues in Cysteine-rich region. Several dehydrogenases share
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Penthiopyrad Here we were able to
2021-07-09

Here, we were able to show for the first time that stimulation of VSMCs with two different growth factors resulted in a dramatic decrease in gp130mRNA expression occurring four to six hours after stimulation with Ang II and PDGF-BB. The mRNA level remained extremely low within 12 hours after stimula
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In the present study we combined activity based protein prof
2021-07-09

In the present study, we combined activity-based protein profiling, biochemical and genetic approaches to identify the PLCPs involved in the sphingolipid pathway leading to plant PCD. By using Arabidopsis Agitoxin 2 and leaves, we demonstrate that this sub-class of plant proteases is activated in
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Several evidences showed that seizures increase brain extrac
2021-07-09

Several evidences showed that seizures increase brain extracellular glutamate, which binds to N-methyl-d-aspartate (NMDA) receptor, then up-regulated cyclooxygenase-2 (COX-2) expression in brain capillaries to increase BBB P-gp expression [11,13,29,30]. A recent study demonstrated a different signal
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br Acknowledgements This work was supported by the National
2021-07-09

Acknowledgements This work was supported by the National Institute of Neurologic Disorders and Stroke (U54 HD061222, 1K23 NS107646-01, and 1K12NS089417-01), Rocky Mountain Rett Association, International Foundation for CDKL5 Research, the Ponzio Family Chair in Neurology Research, and NHMRC Senio
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br Acknowledgments br Introduction to the somatic mitotic ce
2021-07-09

Acknowledgments Introduction to the somatic mitotic cell cycle Cell cycle dysregulation and cancer Structures of the cyclin-dependent protein kinases Structure of the CDK hydrophobic skeletons Classification of protein kinase-drug complexes Dar and Shokat defined three research to
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The co localization of CRF and CCK
2021-07-09

The co-localization of CRF and CCK has been investigated in extensive studies. Sutin and Jacobowitz (1988) examined the immunocytochemical localization of peptides and neurochemicals in the rat laterodorsal tegmental nucleus and found the existence of CRF, atrial natriuretic factor (ANF), neurotensi
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In previous works Wang et al the PR
2021-07-09

In previous works (Wang et al. [4,5]), the PR-CPA EoS has been applied to describe the solubilities of hydrocarbons (including methane, ethane, propane, n-butane, n-pentane, n-hexane, benzene, toluene, and ethyl-benzene) and mercaptans (including methyl mercaptan and ethyl mercaptan) in aqueous MDEA
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To our knowledge immunohistochemical analysis for proGRP was
2021-07-09

To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor adenosine kinase were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with elevated seru
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br DDR receptor and MMP expression Type II collagen
2021-07-09

DDR2 receptor and MMP-13 expression Type II collagen protein in articular cartilage is highly stable structure as its half-life is 117 years [43]. The chondrocytes have limited ability to synthesis type II collagen protein in the matrix of mature articular cartilage once the collagen gets disrupt
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CCR is another chemokine receptor that
2021-07-09

CCR7 is another chemokine receptor that is upregulated in CLL [3], [61], [71], [96] and is believed to play a role in enabling cell entry into lymph nodes [97]. Higher mRNA and protein expression of CCR7 has been observed in unmutated compared to mutated IGHV CLL [46] and increased expression has be
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Considering the divergence of multiple DGAT isoforms we exam
2021-07-08

Considering the divergence of multiple DGAT isoforms, we examined whether MiDGAT1 and MiDGAT2s utilized different fatty acids as the substrate to synthesize TAGs. GC-MS analysis indicated that C16:0 and C18:0 were the major components of TAGs in yeast cells, and all three MiDGATs displayed the same
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Sulfo-NHS-SS-Biotin Collagen compaction and alignment are
2021-07-08

Collagen compaction and alignment are generated by cell-mediated contractile forces (Stopak and Harris, 1982). The transmission of actomyosin forces to collagen has been mainly attributed to integrins and the activation of the Rho-ROCK pathway (Clark et al., 2007, Kural and Billiar, 2013, Provenzano
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The early serologic response of infants to
2021-07-08

The early serologic response of infants to infection with HIV-1 is obscured by the presence of transplacentally acquired maternal HIV antibody. However, the HIV Benidipine HCl australia produced in vitro by peripheral blood from infants has been studied (Pollack et al., 1993) and it has been shown
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In this study we further investigated the involvement of CRF
2021-07-08

In this study, we further investigated the involvement of CRF1 and CRF2 receptors of the dPAG in the regulation of panic-related responses. For this, we used two animal models that associate escape behavior with panic attacks: the elevated T maze and the electrical stimulation of the dPAG (for a ful
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